Noscapine Hydrochloride

CAS: 912-60-7

Ref. TR-N882018

Product Information

• Name: Noscapine Hydrochloride
• Synonyms: 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, hydrochloride (1:1), (3S)-, 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-, hydrochloride, [S-(R*,S*)]-, 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, hydrochloride, (3S)- (9CI), Narcotine, hydrochloride (7CI,8CI), 1,3-Dioxolo[4,5-g]isoquinoline, 1(3H)-isobenzofuranone deriv., Opianine hydrochloride
• Brand: TRC

Description

Applications Noscapine Hydrochloride is a bradykinin B and tubulin inhibitor. Anti-viral.
References Sammeta, S. M., et al.: Pharm. Dev. Technol., 20, 169-175 (2015)

Chemical properties

• Molecular weight: 449.88
• Formula: C₂₂H₂₃NO₇·ClH
• Color/Form: Neat
• InChI: InChI=1S/C22H23NO7.ClH/c1-23-8-7-11-9-14-20(29-10-28-14)21(27-4)15(11)17(23)18-12-5-6-13(25-2)19(26-3)16(12)22(24)30-18;/h5-6,9,17-18H,7-8,10H2,1-4H3;1H/t17-,18+;/m1./s1
• InChI key: InChIKey=MFLVZFXCSKVCSH-URBRKQAFSA-N
• SMILES: COc1ccc2c(c1OC)C(=O)O[C@@H]2[C@H]1c2c(cc3c(c2OC)OCO3)CCN1C.Cl