N-Methyladrenalone Hydrochloride-D3

CAS: 16899-83-5

Ref. TR-N887699

Product Information

• Name: N-Methyladrenalone Hydrochloride-D3
• Synonyms: 2-(bis(methyl-d3)amino)-1-(3,4-dihydroxyphenyl)ethan-1-one hydrochloride, Acetophenone, 3',4'-dihydroxy-2-(dimethylamino)-, hydrochloride, 1-(3,4-Dihydroxyphenyl)-2-(dimethylamino)ethanone hydrochloride, 2-Dimethylamino-3',4'-dihydroxyacetophenone hydrochloride, Acetophenone, 2-dimethylamino-3',4'-dihydroxy-, hydrochloride, Nsc 62512, Ski 28467, U 24274A, Acetophenone, 2-(dimethylamino)-3',4'-dihydroxy-, hydrochloride (8CI), Ethanone, 1-(3,4-dihydroxyphenyl)-2-(dimethylamino)-, hydrochloride (9CI), 2-(3,4-dihydroxyphenyl)-N,N-dimethyl-2-oxoethanaminium chloride, 1-(3,4-Dihydroxyphenyl)-2-(Dimethylamino)Ethanone, 2-(3,4-dihydroxyphenyl)-N,N-dimethyl-2-oxoethanaminium

Description

Applications N-Methyladrenalone Hydrochloride-D3 is a reagent in the synthesis of rac N-Methyl Epinephrine-d6 Hydrochloride (>90%) (M304302) which is the N-methylated analogue of the sympathomimetic hormone Epinephrine (E588585). Recent studies suggest that N-Methylepinephrine may be synthesized from Epinephrine by phenylethanolamine N-methyltransferase present in the brain.
References Kajita, M. et al.: Nip. Iyo Masu Sup. Gak. Kon., 19, 107 (1994); Plummer, C.J. et al.: Eur. J. Med. Chem., 148, 481 (1988);

• Brand: TRC

Chemical properties

• Molecular weight: 237.71
• Formula: C₁₀H₇D₆NO₃•HCl
• Color/Form: Neat
• InChI: InChI=1S/C10H13NO3.ClH/c1-11(2)6-10(14)7-3-4-8(12)9(13)5-7;/h3-5,12-13H,6H2,1-2H3;1H/i1D3,2D3
• InChI key: InChIKey=LVRPQCAWIVYJTP-TXHXQZCNSA-N
• SMILES: Cl.[2H]C([2H])([2H])N(CC(=O)c1ccc(O)c(O)c1)C([2H])([2H])[2H]