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Product Information
Name:
NSC 23766 Trihydrochloride
Synonyms:
- N6-(2-((5-(Diethylamino)pentan-2-yl)amino)-6-methylpyrimidin-4-yl)-2-methylquinoline-4,6-diamine Trihydrochloride
CAS:
Description:
Applications NSC 23766 is a highly soluble and membrane permeable Rac GTPase inhibitor. NSC 23766 inhibits Rac GTPase by targeting Rac activation by guanine nucleotide exchange factor (GEF). NSC 23766 has been shown to inhibit the anchorage-independent growth and invasion phenotypes of human prostate cancer PC-3 cells.
References Gao, Y., et. al.: Proc. Natl. Acad. Sci. U.S.A., 101, 7618, (2004); Akbar, H., et. al.: Methods Enzymol, 406, 554 (2006)
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
530.96
Formula:
C24H38Cl3N7
Color/Form:
Neat
InChI:
InChI=1S/C24H35N7/c1-6-31(7-2)12-8-9-16(3)27-24-28-18(5)14-23(30-24)29-19-10-11-22-20(15-19)21(25)13-17(4)26-22/h10-11,13-16H,6-9,12H2,1-5H3,(H2,25,26)(H2,27,28,29,30)
InChI key:
InChIKey=DEFBCZWQLILOJF-UHFFFAOYSA-N
SMILES:
CCN(CC)CCCC(C)Nc1nc(C)cc(Nc2ccc3nc(C)cc(N)c3c2)n1
MDL:
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EINECS:
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HS code:
Technical inquiry about: TR-N900280 NSC 23766 Trihydrochloride
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