Nystatin

CAS: 1400-61-9

Ref. TR-N926000

Product Information

• Name: Nystatin
• Synonyms: Biofanal, Candio-Hermal, Ceratocide, Diastatin, Flagystatin, Fungicidin, L-Nystatin, Moronal (antibiotic), Myconystatin, Mycostatin, Mycostatin Pastilles, Mykostatyna, Nistatin, Nyotran, Nysfungin, Nystacid, Nystan, Nystavescent, Nystex, Nystop, O-V Statin, Stamycin, (21E,23E,25E,27E,31E,33E)-20-[(3-amino-3,6-dideoxy-D-mannopyranosyl)oxy]-4,6,8,11,12,16,18,36-octahydroxy-35,37,38-trimethyl-2,14-dioxooxacyclooctatriaconta-21,23,25,27,31,33-hexaene-17-carboxylic acid, 33-[(3-Amino-3,6-Dideoxyhexopyranosyl)Oxy]-3,4,7,9,11,17,37-Heptahydroxy-15,16,18-Trimethyl-13-Oxo-14,39-Dioxabicyclo[33.3.1]Nonatriaconta-19,21,25,27,29,31-Hexaene-36-Carboxylic Acid, <span class="text-smallcaps">L</span>-Nystatin, N-[1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl]-4-phenylbutan-2-aminium chloride, Nilstat, Nistatina, Nystatin Suspension Cell Culture Tested, Nystatin, Streptomyces noursei, Sterile, TC Grade, Nystatine, Octadeca-9,11,13,15-Tetraenoic Acid

Description

Applications Polyene antifungal antibiotic complex containing 3 biologically active components, A1, A2, A3. Increases the permeability of the cell membrane of sensitive fungi by binding to sterols. Cell culture tested. Growth promotant.Nystatin A1 is shown.
References Brautaset, T., et al.: Chem. Biol., 7, 395 (2000), Brautaset, T., et al.: J. Biol. Chem., 278, 14913 (2003), Bruheim, P., et al.: Antimicrob. Agents Chemother., 48, 4120 (2004), Scott, L., et al.: Drugs, 67, 269 (2007),

• Brand: TRC

Chemical properties

• Molecular weight: 926.09
• Formula: C₄₇H₇₅NO₁₇
• Color/Form: Neat
• InChI: InChI=1S/C47H75NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-36(53)35(52)20-19-31(49)21-32(50)22-33(51)23-39(55)62-29(3)28(2)42(27)56/h5-6,8,10-18,27-38,40-44,46,49-54,56-58,61H,7,9,19-26,48H2,1-4H3,(H,59,60)/b6-5+,10-8+,13-11+,14-12+,17-15+,18-16+/t27?,28?,29?,30?,31?,32?,33?,34?,35?,36?,37?,38?,40?,41-,42+,43+,44-,46+,47+/m0/s1
• InChI key: InChIKey=VQOXZBDYSJBXMA-HWEHLMELSA-N
• SMILES: CC1C=CC=CCCC=CC=CC=CC=CC(OC2OC(C)C(O)C(N)C2O)CC2OC(O)(CC(O)C(O)CCC(O)CC(O)CC(O)CC(=O)OC(C)C(C)C1O)CC(O)C2C(=O)O