
Octyl-α-hydroxyglutarate
Ref. TR-O287590
100mg
3,477.00€

Product Information
Name:Octyl-α-hydroxyglutarate
Controlled Product
Synonyms:
- Octyl-2-HG
Brand:TRC
Description:Applications Octyl-α-hydroxyglutarate is a cell-permeable derivative of 2-HG (α-hydroxyglutaric acid). Mutations in isocitrate dehydrogenase 1 (IDH1 and IDH2) associated with certain cancers cause isocitrate to metabolize into 2-HG as opposed α-ketoglutarate, inhibiting α-ketoglutarate-dependant dioxygenases including lysine demethylases and DNA hydroxylases. This compound is suitable for IDH (isocitrate dehydrogenase) related research.References Struys, E. et al.: Clin. Chem., 49, 1133 (2003); Ward, P. et al.: Cancer Cell., 17, 225 (2010);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:260.327
Formula:C13H24O5
Color/Form:Neat
InChI:InChI=1S/C13H24O5/c1-2-3-4-5-6-7-10-18-13(17)11(14)8-9-12(15)16/h11,14H,2-10H2,1H3,(H,15,16)
InChI key:InChIKey=UJZOKTKSGUOCCM-UHFFFAOYSA-N
SMILES:CCCCCCCCOC(=O)C(O)CCC(=O)O
Technical inquiry about: Octyl-α-hydroxyglutarate
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