Olopatadine N-Oxide

CAS: 203188-31-2

Ref. TR-O575010

Product Information

• Name: Olopatadine N-Oxide
• Synonyms: (Z)-3-{2-(carboxymethyl)dibenzo[b,e]oxepin-11(6H)-ylidene}-N,N-dimethylpropan-1-amine oxide, Olopatadine Related Compound B

Description

Impurity Olopatadine USP Related Compound B
Applications A metabolite of Olopatadine (M3). A dibenz[b,e]oxepin derivative as antiallergic agents, useful for treatment of asthma, allergic rhinitis, atopic dermatitis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Mizuno, N., et al.: Drug Metabol. Pharmacokin., 17, 93 (2002), Polli, J., et al.: J. Pharm. Sci., 92, 2082 (2003), Tashiro, M., et al.: J. Clin. Pharmacol., 44, 890 (2004), Ohashi, R., et al.: Drug Metab. Disos., 34, 793 (2006),

• Brand: TRC

Chemical properties

• Molecular weight: 353.41
• Formula: C₂₁H₂₃NO₄
• Color/Form: Neat
• InChI: InChI=1S/C21H23NO4/c1-22(2,25)11-5-8-18-17-7-4-3-6-16(17)14-26-20-10-9-15(12-19(18)20)13-21(23)24/h3-4,6-10,12H,5,11,13-14H2,1-2H3,(H,23,24)/b18-8-
• InChI key: InChIKey=TXKZPVWYFNGMCP-LSCVHKIXSA-N
• SMILES: C[N+](C)([O-])CC/C=C1/c2ccccc2COc2ccc(CC(=O)O)cc21