Product Information
- 1H-Benz[de]isoquinolin-1-one
- 2-(3R)-1-azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-
- hydrochloride (1:1)
- (3aR)-
- 1H-Benz[de]isoquinolin-1-one
- 2-(1-azabicyclo[2.2.2]oct-3-yl)-2,3,3a,4,5,6-hexahydro-
- monohydrochloride
- [R-(R*,R*)]- (9CI)
- (3aR)-2-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-1H-benz[de]isoquinolin-1-one hydrochloride (1:1)
- RS 25259-198
- See more synonyms
- S-(-)-3-Aminoquinuclidine 2HCl
- (3aR)-2-[(3S)-1-azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one
- (3R)-3-ammonio-1-azoniabicyclo[2.2.2]octane dichloride
- (3aS)-2-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one
- (S)-(-)-3-Amino Quinuclidine Dihcl
Applications Serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.
References Clark, R.D., et al.: J. Med. Chem., 36, 2645 (1993), Wong, E.H.F., et al.: Br. J. Pharmacol., 114, 851 (1995), Grunberg, S.M., et al.: Expert. Opin. Pharmacother., 4, 2297 (2003), Eisenberg, P., et al.: Ann. Oncol., 15, 330 (2004), Siddiqui, M.A.A., et al.: Drugs, 64, 1125 (2004),
Chemical properties
Technical inquiry about: TR-P165805 (R,R)-Palonosetron Hydrochloride
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