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Palonosetron-3-ene N-Oxide
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Palonosetron-3-ene N-Oxide

CAS: 1021456-82-5

Ref. TR-P165820

10mg
368.00 €
100mg
2,504.00 €
Estimated delivery in United States, on Wednesday 15 Jan 2025

Product Information

Name:
Palonosetron-3-ene N-Oxide
Controlled Product
Synonyms:
  • 1H-Benz[de]isoquinolin-1-one
  • 2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-
  • 2,4,5,6-Tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-1H-benz[de]isoquinolin-1-one
Description:

Applications Palonosetron-3-ene N-Oxide is an impurity of Palonosetron (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.
References Clark, R.D., et al.: J. Med. Chem., 36, 2645 (1993); Wong, E.H.F., et al.: Br. J. Pharmacol., 114, 851 (1995); Grunberg, S.M., et al.: Expert. Opin. Pharmacother., 4, 2297 (2003); Eisenberg, P., et al.: Ann. Oncol., 15, 330 (2004); Siddiqui, M.A.A., et al.: Drugs, 64, 1125 (2004)

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:

Chemical properties

Molecular weight:
310.39
Formula:
C19H22N2O2
Color/Form:
Neat
InChI:
InChI=1S/C19H22N2O2/c22-19-16-6-2-4-14-3-1-5-15(18(14)16)11-20(19)17-12-21(23)9-7-13(17)8-10-21/h2,4,6,11,13,17H,1,3,5,7-10,12H2/t13?,17-,21?/m1/s1
InChI key:
InChIKey=UJTMVWDDYCEVNT-IBBFCSCYSA-N
SMILES:
O=c1c2cccc3c2c(cn1[C@H]1C[N+]2([O-])CCC1CC2)CCC3
MDL:
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EINECS:
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Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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