Pamoic Acid

CAS: 130-85-8

Ref. TR-P173500

Product Information

• Name: Pamoic Acid
• Synonyms: 4,4'-Methylenebis[3-hydroxy-2-naphthalenecarboxylic acid], 2-Naphthoic acid, 4,4'-methylenebis[3-hydroxy- (6CI,7CI,8CI), 4,4'-Methylenebis[3-hydroxy-2-naphthalenecarboxylic acid], 2,2'-Dihydroxy-1,1'-dinaphthylmethane-3,3'-dicarboxylic acid, 4,4'-Methylenebis(3-hydroxy-2-naphthalenecarboxylic acid), 4,4'-Methylenebis[3-hydroxy-2-naphthoic acid], 4-[(3-Carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic acid, Bis(2-hydroxy-3-carboxy-1-naphthyl)methane, Embonic acid, KG 122, NSC 30188, NSC 40132, 2,2-Dihydroxy-1,1-Dinaphthylmethane-3,3-Dicarboxylic Acid, 2-Naphthalenecarboxylic acid, 4,4′-methylenebis[3-hydroxy-, 2-Naphthoic acid, 4,4′-methylenebis[3-hydroxy-, 3,3-Dihydroxy-4,4-Methylenedi(2-Naphthoic Acid), 4,4'-Methanediylbis(3-Hydroxynaphthalene-2-Carboxylate), 4,4'-Methanediylbis(3-Hydroxynaphthalene-2-Carboxylic Acid), 4,4-Methylenebis[3-hydroxy-2-naphthalenecarboxylic acid], 4,4′-Methylenebis[3-hydroxy-2-naphthoic acid], Dilithium 4,4'-Methanediylbis(3-Hydroxynaphthalene-2-Carboxylate), Embonic acid~4,4-Methylenebis(3-hydroxy-2-naphthoic acid), Kg 122

Description

Applications Agonist of the orphan G protein-coupled receptor GPR35: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity. Used as an inhibitor in the real-time fluorescence enzymatic characterization study of specialized human DNA polymerases.
References Zhao, P. et al.: Mol. Pharmacol., 78, 560 (2010); Dorjsujen, D. et al.: Nuc. Acids Res., 37, e128 (2009);

• Brand: TRC

Chemical properties

• Molecular weight: 388.37
• Formula: C₂₃H₁₆O₆
• Color/Form: Neat
• InChI: InChI=1S/C23H16O6/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29/h1-10,24-25H,11H2,(H,26,27)(H,28,29)
• InChI key: InChIKey=WLJNZVDCPSBLRP-UHFFFAOYSA-N
• SMILES: O=C(O)c1cc2ccccc2c(Cc2c(O)c(C(=O)O)cc3ccccc23)c1O