Paramethasone

CAS: 53-33-8

Ref. TR-P191840

Product Information

• Name: Paramethasone
• Synonyms: Pregna-1,4-diene-3,20-dione, 6-fluoro-11,17,21-trihydroxy-16-methyl-, (6a,11ß,16a)-, Pregna-1,4-diene-3,20-dione, 6a-fluoro-11ß,17,21-trihydroxy-16-methyl- (7CI), Pregna-1,4-diene-3,20-dione, 6a-fluoro-11ß,17,21-trihydroxy-16a-methyl- (8CI), (6a,11ß,16a)-6-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 16a-Methyl-6a-fluoroprednisolone, 6a-Fluoro-11ß,17a,21-trihydroxy-16a-methyl-1,4-pregnadiene-3,20-dione, 6a-Fluoro-16a-methylprednisolone, Cortiden, (6α,11β,16α)-6-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 16α-Methyl-6α-fluoroprednisolone, 6α-Fluoro-11β,17α,21-trihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione, 6α-Fluoro-16α-methylprednisolone, Parametasona, Paramethason, Pregna-1,4-diene-3,20-dione, 6α-fluoro-11β,17,21-trihydroxy-16-methyl-, Pregna-1,4-diene-3,20-dione, 6α-fluoro-11β,17,21-trihydroxy-16α-methyl-

Description

Applications Paramethasone, is a fluorinated glucocorticoid, having anti-inflammatory and immunosuppressant properties.
References Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995), Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999), Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999);

• Brand: TRC

Chemical properties

• Molecular weight: 392.46
• Formula: C₂₂H₂₉FO₅
• Color/Form: White To Beige
• InChI: InChI=1S/C22H29FO5/c1-11-6-14-13-8-16(23)15-7-12(25)4-5-20(15,2)19(13)17(26)9-21(14,3)22(11,28)18(27)10-24/h4-5,7,11,13-14,16-17,19,24,26,28H,6,8-10H2,1-3H3/t11-,13+,14+,16+,17+,19-,20+,21+,22+/m1/s1
• InChI key: InChIKey=MKPDWECBUAZOHP-ULHLPKEOSA-N
• SMILES: C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@@]4(C)[C@H]3[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO