Paramethasone Acetate

CAS: 1597-82-6

Ref. TR-P191845

Product Information

• Name: Paramethasone Acetate
• Synonyms: Alondra, Cortidene, Dilar, Dillar, Flumethone, Haldrate, Haldrone, Metilar, Monocortin, Paramethasone 21-acetate, Paramezone, Stemex, Syntecort, Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-6-fluoro-11,17-dihydroxy-16-methyl-, (6alpha,11beta,16alpha)-, Pregna-1,4-diene-3,20-dione, 6alpha-fluoro-11beta,17,21-trihydroxy-16alpha-methyl-, 21-acetate (6CI,7CI,8CI), 16alpha-Methyl-6alpha-fluoroprednisolone 21-acetate, 21-Acetoxy-6alpha-fluoro-11beta,17-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione, 21-Acetyl-6alpha-fluoro-16alpha-methylprednisolone, 6alpha-Fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-acetate, 6alpha-Fluoro-16alpha-methylprednisolone 21-acetate, (6Alpha,11Beta,16Alpha)-6-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Acetate, (6Alpha,8Xi,9Xi,10Xi,11Beta,13Xi,16Alpha)-6-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Acetate, (6α,11β,16α)-21-(Acetyloxy)-6-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione, 16α-Methyl-6α-fluoroprednisolone 21-acetate, 21-Acetoxy-6α-fluoro-11β,17-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione, 21-Acetyl-6α-fluoro-16α-methylprednisolone, 6α-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-acetate, 6α-Fluoro-16α-methylprednisolone 21-acetate, Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-6-fluoro-11,17-dihydroxy-16-methyl-, (6α,11β,16α)-, Pregna-1,4-diene-3,20-dione, 6α-fluoro-11β,17,21-trihydroxy-16α-methyl-, 21-acetate

Description

Applications Paramethasone Acetate, is a derivative of Dexamethasone (D298800), a potent synthetic member of the glucocorticoid class of steroid drugs that has anti-inflammatory and immunosuppressant properties.
References Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995), Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999), Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999)

• Brand: TRC

Chemical properties

• Molecular weight: 434.50
• Formula: C₂₄H₃₁FO₆
• Color/Form: White To Off-White
• InChI: InChI=1S/C24H31FO6/c1-12-7-16-15-9-18(25)17-8-14(27)5-6-22(17,3)21(15)19(28)10-23(16,4)24(12,30)20(29)11-31-13(2)26/h5-6,8,12,15-16,18-19,21,28,30H,7,9-11H2,1-4H3/t12-,15+,16+,18+,19+,21-,22+,23+,24+/m1/s1
• InChI key: InChIKey=HYRKAAMZBDSJFJ-LFDBJOOHSA-N
• SMILES: CC(=O)OCC(=O)[C@@]1(O)[C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C