Pazopanib Hydrochloride

CAS: 635702-64-6

Ref. TR-P210926

Product Information

• Name: Pazopanib Hydrochloride
• Synonyms: Benzenesulfonamide, 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-, hydrochloride (1:1), Benzenesulfonamide, 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-, monohydrochloride (9CI), 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide hydrochloride, GW 786034B, GW 786034B, 5-((4-((2,3-Dimethyl-2H-indazol-6-yl)methylamino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonamide monohydrochloride, 5-(4-((2,3-dimethyl-2H-indazol-6-yl)(Methyl)amino)pyrimidin-2-ylamino)-2-Methylbenzenesulfonamide hydrochloride, Benzenesulfonamide, 5-((4-((2,3-dimethyl-2H-indazol-6-yl)methylamino)-2-pyrimidinyl)amino)-2-methyl-,monohydrochloride, Benzenesulfonamide, 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-, hydrochloride (1:1), Gw 786034B, Gw786034B, Pazopanib HCl, Unii-33Y9Anm545, Votrient

Description

Applications The Hydrochloride salt of Pazopanib (P210925) a oral angiogenesis inhibitor targeting VEGFR and PDGFR.
References Sleijfer, S., et al.: J. Clin. Oncol., 27, 3126 (2009), Chan, A., et al.: Drugs, 69, 167 (2009),

• Brand: TRC

Chemical properties

• Molecular weight: 473.98
• Formula: C₂₁H₂₃N₇O₂S·ClH
• Color/Form: Off-White
• InChI: 1H, /h5-12H,1-4H3,(H2,22,29,30)(H,23,24,25), InChI=1S/C21H23N7O2S.ClH/c1-13-5-6-15(11-19(13)31(22,29)30)24-21-23-10-9-20(25-21)27(3)16-7-8-17-14(2)28(4)26-18(17)12-16
• InChI key: InChIKey=MQHIQUBXFFAOMK-UHFFFAOYSA-N
• SMILES: Cc1ccc(Nc2nccc(N(C)c3ccc4c(C)n(C)nc4c3)n2)cc1S(N)(=O)=O.Cl