Product Information
Name:PD-173074
Controlled Product
Synonyms:
- N-[2-[[4-(Diethylamino)butyl]amino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea
- PF-01367255
Brand:TRC
Description:Applications PD 173074 is a selective FGFR1 and FGFR3 inhibitor. PD 173074 is a compound induced a dose-dependent reduce in cell viability and an increase in apoptosis, accompanied by a decrease in extracellular signal-related kinase phosphorylation.References Mohammadi, M., et al.: Science, 276, 955 (1997), Yagasaki, F., et al.: Cancer Res., 61, 8371 (2001), Keats, J., et al.: Blood, 101, 1520 (2003), Buchler, et al.: 9, 119 (2007),
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:523.67
Formula:C28H41N7O3
Color/Form:Neat
InChI:InChI=1S/C28H41N7O3/c1-8-35(9-2)13-11-10-12-29-26-30-18-20-16-23(19-14-21(37-6)17-22(15-19)38-7)25(31-24(20)32-26)33-27(36)34-28(3,4)5/h14-18H,8-13H2,1-7H3,(H3,29,30,31,32,33,34,36)
InChI key:InChIKey=DXCUKNQANPLTEJ-UHFFFAOYSA-N
SMILES:CCN(CC)CCCCN=c1ncc2cc(-c3cc(OC)cc(OC)c3)c(NC(=O)NC(C)(C)C)nc2[nH]1
Technical inquiry about: PD-173074
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