Product Information
Name:PD-173952
Controlled Product
Synonyms:
- 6-(2,6-Dichlorophenyl)-8-methyl-2-[[4-(4-morpholinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one
Brand:TRC
Description:Applications PD-173952 is a Bcr-Abl tyrosine kinase inhibitor used in treatment research for chronic myelegenous leukemia (CML).References Dorsey, J.F. et al.: Leukemia, 16, 1589 (2002); Wisniewski, D. et al.: Canc. Res., 62, 4244 (2002); Mizenina, O.A. et al.: Cell Cycle, 3, 796 (2004);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:482.36
Formula:C24H21Cl2N5O2
Color/Form:Neat
InChI:InChI=1S/C24H21Cl2N5O2/c1-30-22-15(13-18(23(30)32)21-19(25)3-2-4-20(21)26)14-27-24(29-22)28-16-5-7-17(8-6-16)31-9-11-33-12-10-31/h2-8,13-14H,9-12H2,1H3,(H,27,28,29)
InChI key:InChIKey=XZEJMVDCQZRHLN-UHFFFAOYSA-N
SMILES:Cn1c(=O)c(-c2c(Cl)cccc2Cl)cc2cnc(Nc3ccc(N4CCOCC4)cc3)nc21
Technical inquiry about: PD-173952
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