Product Information
Name:PD-184161
Controlled Product
Synonyms:
- 5-Bromo-2-[(2-chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluorobenzamide
Brand:TRC
Description:Applications PD-184161 is a novel mitogen-activated protein kinase kinase (MEK) inhibitor shown to exhibit antitumor effects and suppress MEK-extracellular signal-related kinase signaling activity and cell proliferation in human hepatocellular carcinoma cells and in human hepatocellular carcinoma xenografts. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageReferences Yip-Schneider, M.T. et al.: J. Pharmacol. Exp. Therap., 329, 1063 (2009); Klein, P.J. et al.: Neoplasia, 8, 1 (2006); Yung, H.W. et al.: Biochem. Pharmacol., 68, 351 (2004);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:557.5556
Formula:C17H13BrClF2IN2O2
Color/Form:Neat
InChI:InChI=1S/C17H13BrClF2IN2O2/c18-11-6-10(17(25)24-26-7-8-1-2-8)16(15(21)14(11)20)23-13-4-3-9(22)5-12(13)19/h3-6,8,23H,1-2,7H2,(H,24,25)
InChI key:InChIKey=VJNZMSLGVUSPCF-UHFFFAOYSA-N
SMILES:O=C(NOCC1CC1)c1cc(Br)c(F)c(F)c1Nc1ccc(I)cc1Cl
Technical inquiry about: PD-184161
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