Pentostatin

CAS: 53910-25-1

Ref. TR-P227350

Product Information

• Name: Pentostatin
• Synonyms: Imidazo[4,5-d][1,3]diazepin-8-ol, 3-(2-deoxy-ß-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydro-, (8R)-, Imidazo[4,5-d][1,3]diazepin-8-ol, 3-(2-deoxy-ß-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydro-, (R)-, 2'-DCF, 2'-Deoxycoformycin, 2'-Dexoycoformycin, CI 825, CL 67310465, Cl 825, Co-V, Co-Vidarabine, Coforin, Deaminase inhibitor, Deoxycoformycin, NSC 218321, NSC 247520, Nipent, PD-ADI, Vira A deaminase inhibitor, (8R)-3-(2-Deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-3,4,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol, (8R)-3-(2-deoxy-beta-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol, (8R)-3-[(4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-7,8-dihydro-4H-imidazo[4,5-f][1,3]diazepin-8-ol, (R)-3-(2-Deoxy-Beta-D-Erythro-Pento-Furanosyl)-3,6,7,8-Tetrahydroimidazo[4,5-D, (R)-3-(2-Deoxy-Beta-D-Pentofuranosyl)-3,6,7,8-Tetrahydroimidazo(4,5-D)(1,3)D, (R)-Deoxycoformycin, (R)-Rahydro, 2'-Dcf, 2’-Deoxycoformycin, 2’Dcf, Ci-825, Cl 67310465, Imidazo[4,5-d][1,3]diazepin-8-ol, 3-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-3,4,7,8-tetrahydro-, (8R)-, Imidazo[4,5-d][1,3]diazepin-8-ol, 3-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-3,4,7,8-tetrahydro-, (R)-, Imidazo[4,5-d][1,3]diazepin-8-ol, 3-(2-deoxy-β-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydro-, (8R)-, Imidazo[4,5-d][1,3]diazepin-8-ol, 3-(2-deoxy-β-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydro-, (R)-, Nsc 218321, Nsc 247520, Pd-Adi, (8R)-3-(2-Deoxy-β-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol

Description

Applications An adenosine deaminase inhibitor used as an anti-cancer therapeutic drug. Shown to be effective in the treatment of hairy cell leukemia as well as having use in the treatment of other types of cancer such as chronic lymphocytic leukemia.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Rogler-Brown, T. et al.: Biochem. Pharmacol., 28, 201 (1979); Johnston, J.B. et al.: J. Natl. Canvcer Inst., 80, 765 (1988); Fortune, A.F. et al.: Leuk. and Lymph., 51, 839 (2010); Robak, T. et al.: Drugs, 69, 2415 (2009);

• Brand: TRC

Chemical properties

• Molecular weight: 268.27
• Formula: C₁₁H₁₆N₄O₄
• Color/Form: White To Off-White
• InChI: InChI=1S/C11H16N4O4/c16-3-8-6(17)1-9(19-8)15-5-14-10-7(18)2-12-4-13-11(10)15/h4-9,16-18H,1-3H2,(H,12,13)/t6-,7+,8+,9+/m0/s1
• InChI key: InChIKey=QINRQIZOBCQKAZ-UHFFFAOYSA-N
• SMILES: CCOC(=O)c1cnc(SC)nc1N