Product Information
Name:PF 3845
Controlled Product
Synonyms:
- N-3-Pyridinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methyl]-1-piperidinecarboxamide
Brand:TRC
Description:Applications PF 3845 is a selective fatty acid amide hydrolase (FAAH) inhibitor (Ki = 0.23 μM). Reduces inflammatory pain via a cannabinoid receptor-dependent mechanism. Highly efficacious and selective in vivo. Displays no activity at FAAH-2 (IC50 >10 μM). Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageReferences Ahn, et al.: Chem. Biol., 16, 411 (2009), Ahn, et al.: Expert. Opin. Drug Discov., 4 763 (2009),
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:456.46
Formula:C24H23F3N4O2
Color/Form:Neat
InChI:InChI=1S/C24H23F3N4O2/c25-24(26,27)19-6-7-22(29-15-19)33-21-5-1-3-18(14-21)13-17-8-11-31(12-9-17)23(32)30-20-4-2-10-28-16-20/h1-7,10,14-17H,8-9,11-13H2,(H,30,32)
InChI key:InChIKey=NBOJHRYUGLRASX-UHFFFAOYSA-N
SMILES:O=C(Nc1cccnc1)N1CCC(Cc2cccc(Oc3ccc(C(F)(F)F)cn3)c2)CC1
Technical inquiry about: PF 3845
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