Estimated delivery in United States, on Thursday 20 Jun 2024
Product Information
Name:
PF-562271
Controlled Product
Synonyms:
- N-[3-[[[2-[(2,3-Dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]-2-pyridinyl]-N-methyl-methanesulfonamide
- N-Methyl-N-[3-[[[2-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]-5-trifluoromethylpyrimidin-4-yl]amino]methyl]pyridin-2-yl]methanesulfonamide
- Pf 562271
- Pf-00562271
CAS:
Description:
Applications PF-56227 is a potent, ATP-competitive, reversible inhibitor of focal adhesion kinase (FAK). Potent FAK inhibitor.
References Infante, J., et al.: J. Clin. Oncol., 30, 1527 (2012); Lee, B., et al.: Mol. Cancer Ther., 13, 190 (2014)
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
507.49
Formula:
C21H20F3N7O3S
Color/Form:
White to Off-White Solid
InChI:
InChI=1S/C21H20F3N7O3S/c1-31(35(2,33)34)19-12(4-3-7-25-19)10-26-18-15(21(22,23)24)11-27-20(30-18)28-14-5-6-16-13(8-14)9-17(32)29-16/h3-8,11H,9-10H2,1-2H3,(H,29,32)(H2,26,27,28,30)
InChI key:
InChIKey=MZDKLVOWGIOKTN-UHFFFAOYSA-N
SMILES:
CN(c1ncccc1CNc1nc(Nc2ccc3c(c2)CC(=O)N3)ncc1C(F)(F)F)S(C)(=O)=O
MDL:
Melting point:
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Flash point:
Density:
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EINECS:
Merck:
HS code:
Technical inquiry about: TR-P293920 PF-562271
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