Product Information
Name:
PFK 15
Synonyms:
- 1-(4-Pyridinyl)-3-(2-quinolinyl)-2-propen-1-one
Description:
Applications PFK 15 is a novel inhibitor of glycolytic enzyme 6-phosphofructo-2-kinase/2,6-bisphosphatase 3 (PFKFB3). It suppresses the glucose uptake and growth of Lewis lung carcinomas in syngeneic mice, and induces apoptosis in abnormal cells.
References Clem, B., et al.: Mol. Cancer Ther., 12, 1461 (2013); Brooke, D., et al.: Bioorg. Med. Chem., 22, 1029 (2014);
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
260.29
Formula:
C17H12N2O
Color/Form:
Light Beige to Beige Solid
InChI:
InChI=1S/C17H12N2O/c20-17(14-9-11-18-12-10-14)8-7-15-6-5-13-3-1-2-4-16(13)19-15/h1-12H/b8-7+
InChI key:
InChIKey=UJJUKZPBUMCSJZ-BQYQJAHWSA-N
SMILES:
O=C(/C=C/c1ccc2ccccc2n1)c1ccncc1
MDL:
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