Phenazocine

CAS: 127-35-5

Ref. TR-P295400

Product Information

• Name: Phenazocine
• Synonyms: 1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-(2-phenylethyl)-2,6-methano-3-benzazocin-8-ol, 1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-phenethyl-2,6-methano-3-benzazocin-8-ol, 2'-Hydroxy-5,9-dimethyl-2-phenethyl-6,7-benzomorphan, Phenethylazocine, Phenobenzorphan, (2R,6R,11R)-6,11-dimethyl-3-(2-phenylethyl)-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-8-ol, 1,2,3,4,5,6-Hexahydro-6,11-Dimethyl-3-Phenethyl-2,6-Methano-3-Benzazocin-8-Ol, 2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(2-phenylethyl)-, 2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-phenethyl-, 2′-Hydroxy-5,9-dimethyl-2-phenethyl-6,7-benzomorphan, 6,11-Dimethyl-3-(2-Phenylethyl)-1,2,3,4,5,6-Hexahydro-2,6-Methano-3-Benzazocin-8-Ol

Description

Applications Phenazocine is an opioid analgesic drug related to Pentazocine (P274300) and has a similar profile of effects. The use of Phenazocine results in analgesia and euphoria and in some cases dysphoria and hallucinations at high doses, most likely due to action at κ-opioid and σ receptors. Phenazocine is a much more potent analgesic than morphine with about 4 times the potency and very little side effects making it a better treatment option for biliary or pancreatic pain.Controlled Substance.
References Hopton, D., et al.: Gut, 12, 51 (1971); Eckenhoff, J.E., et al.: Anesthesiology, 20, 355 (1959); Clarke, E.G., et al.: Nature, 184, 451 (1959);

• Brand: TRC

Chemical properties

• Molecular weight: 321.46
• Formula: C₂₂H₂₇NO
• Color/Form: Neat
• InChI: InChI=1S/C22H27NO/c1-16-21-14-18-8-9-19(24)15-20(18)22(16,2)11-13-23(21)12-10-17-6-4-3-5-7-17/h3-9,15-16,21,24H,10-14H2,1-2H3
• InChI key: InChIKey=ZQHYKVKNPWDQSL-UHFFFAOYSA-N
• SMILES: CC1C2Cc3ccc(O)cc3C1(C)CCN2CCc1ccccc1