(AlphaR)-α-Phenyl-2-piperidinemethanol

Ref. TR-P336335

Product Information

• Name: (AlphaR)-α-Phenyl-2-piperidinemethanol
• Synonyms: (1R)-phenyl(piperidin-2-yl)methanol
• Brand: TRC
• Description: Applications (αR)- α-Phenyl-2-piperidinemethanol is an intermediate in the synthesis of Levophacetoperane Hyrochloride (L376470), which is a sympathomimetic central nervous system stimulant and is commonly used to treat depression. Levophacetoperane is also a known analeptic and is strongly linked to apnea reversal in dogs after a single intravenous injection.References Dobkin, A. B.: Anaesthesia, 15, 146 (1960); Dugal, R., et al.: J. Anal. Toxicol., 2, 101 (1978)

Chemical properties

• Molecular weight: 191.27
• Formula: C₁₂H₁₇NO
• Color/Form: Neat
• InChI: InChI=1S/C12H17NO/c14-12(10-6-2-1-3-7-10)11-8-4-5-9-13-11/h1-3,6-7,11-14H,4-5,8-9H2/t11?,12-/m1/s1
• InChI key: InChIKey=SDTUDGBCOQLTPT-LCBBPUETSA-N
• SMILES: CC(=O)OCC1O[C@@H](Oc2ccc3c(C)cc(=O)oc3c2)C(O)C(OC(C)=O)[C@H]1OC(C)=O