1-Phenyl-5-(pyridin-2-yl)-2(1H)-pyridone-d5

CAS: 2733718-04-0

Ref. TR-P336752

Product Information

• Name: 1-Phenyl-5-(pyridin-2-yl)-2(1H)-pyridone-d5
• Synonyms: 1'-Phenyl[2,3'-bipyridin]-6'(1'H)-one-d5, 5-(2-Pyridyl)-1-phenyl-1,2-dihydropyridin-2-one-d5
• Brand: TRC

Description

Applications 1-Phenyl-5-(pyridin-2-yl)-2(1H)-pyridone-d5 is an intermediate in the synthesis of Perampanel-d5, which is the labeled analogue of Perampanel (P285520), an antiepileptic drug.
References Shih, J., et al.: Therap. Clinical Risk Management, 9, 285 (2013); Rogawski, M. A., et al.: Epilepsy Curr., 11, 56 (2011);

Chemical properties

• Molecular weight: 253.31
• Formula: C₁₆D₅H₇N₂O
• Color/Form: Neat
• InChI: InChI=1S/C16H12N2O/c19-16-10-9-13(15-8-4-5-11-17-15)12-18(16)14-6-2-1-3-7-14/h1-12H/i1D,2D,3D,6D,7D
• InChI key: InChIKey=JHBMGQOABUXDND-FSTBWYLISA-N
• SMILES: [2H]c1c([2H])c([2H])c(-n2cc(-c3ccccn3)ccc2=O)c([2H])c1[2H]