Pholcodine

CAS: 509-67-1

Ref. TR-P351500

Product Information

• Name: Pholcodine
• Synonyms: Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-17-methyl-3-[2-(4-morpholinyl)ethoxy]-, (5a,6a)-, Morphinan-6a-ol, 7,8-didehydro-4,5a-epoxy-17-methyl-3-(2-morpholinoethoxy)- (8CI), Morphine, 3-O-(2-morpholinoethyl)- (7CI), Morphine, O3-(2-morpholinoethyl)- (6CI), (5a,6a)-7,8-Didehydro-4,5-epoxy-17-methyl-3-[2-(4-morpholinyl)ethoxy]morphinan-6-ol, 3-[2-(4-Morpholinyl)ethyl]morphine, Biocalyptol, Codylin, Ethnine, Folcodin, Folcodine, Galenphol, Galphol, Glycodine, Hibernyl, Homocodeine, Memine, Morpholinylethylmorphine, Neocodine, O-2-Morpholinoethylmorphine, O3-(2-Morpholinoethyl)morphine, Pectolin, Pholtex, Tussokon, Tuxi, Tuxi Forte, Weifacodine, ß-Morpholinylethylmorphine, (5Alpha,6Alpha)-17-Methyl-3-(2-Morpholin-4-Ylethoxy)-7,8-Didehydro-4,5-Epoxymorphinan-6-Ol, (5α,6α)-7,8-Didehydro-4,5-epoxy-17-methyl-3-[2-(4-morpholinyl)ethoxy]morphinan-6-ol, Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-17-methyl-3-[2-(4-morpholinyl)ethoxy]-, (5α,6α)-, Morphinan-6α-ol, 7,8-didehydro-4,5α-epoxy-17-methyl-3-(2-morpholinoethoxy)-, Morphine, 3-O-(2-morpholinoethyl)-, Morphine, O³-(2-morpholinoethyl)-, O3-(2-morpholinoethyl)morphine, O³-(2-Morpholinoethyl)morphine, Pholcodine (PI), β-Morpholinylethylmorphine

Description

Applications Antitussive; an opioid cough suppressant. Controlled Substance.
References Findlay, J.W.A.: J. Clin. Pharm. Therap., 13, 5 (1988); Chen, Z.R. et al.: Br. J. Clin. Pharmacol., 26, 445 (1988); Maurer, H.H. et al.: Arzneim.-Forsch., 40, 546 (1990);

• Brand: TRC

Chemical properties

• Molecular weight: 398.50
• Formula: C₂₃H₃₀N₂O₄
• Color/Form: Neat
• InChI: InChI=1S/C23H30N2O4/c1-24-7-6-23-16-3-4-18(26)22(23)29-21-19(5-2-15(20(21)23)14-17(16)24)28-13-10-25-8-11-27-12-9-25/h2-5,16-18,22,26H,6-14H2,1H3/t16-,17+,18-,22-,23-/m0/s1
• InChI key: InChIKey=GPFAJKDEDBRFOS-FKQDBXSBSA-N
• SMILES: CN1CC[C@]23c4c5ccc(OCCN6CCOCC6)c4O[C@H]2[C@@H](O)C=C[C@H]3[C@H]1C5