4-(3-Phenyl-4,4-dimethyl-5-oxo-2-thioxoimidazolidin-1-yl)-2-trifluoromethylbenzonitrile
CAS:
Ref. TR-P356890
500mg
1,022.00€
Product Information
Name:4-(3-Phenyl-4,4-dimethyl-5-oxo-2-thioxoimidazolidin-1-yl)-2-trifluoromethylbenzonitrile
Controlled Product
Synonyms:
- 4-(4,4-Dimethyl-5-oxo-3-phenyl-2-thioxo-1-imidazolidinyl)-2-(trifluoromethyl)benzonitrile
Brand:TRC
Description:Applications 4-(3-Phenyl-4,4-dimethyl-5-oxo-2-thioxoimidazolidin-1-yl)-2-trifluoromethylbenzonitrile is used in the preparation of androgen receptor pure antagonist (CH5137291) for the treatment of castration-resistant prostate cancer.References Yoshino, Hitoshi. et al.,Bioorg. Med. Chem. 18,8150-8157(2010);
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Chemical properties
Molecular weight:389.394
Formula:C19H14F3N3OS
Color/Form:Neat
InChI:InChI=1S/C19H14F3N3OS/c1-18(2)16(26)24(17(27)25(18)13-6-4-3-5-7-13)14-9-8-12(11-23)15(10-14)19(20,21)22/h3-10H,1-2H3
SMILES:CC1(C)C(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C(=S)N1c1ccccc1
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