Product Information
Name:Pimozide
Controlled Product
Synonyms:
- 2H-Benzimidazol-2-one
- 1-[1-[4,4-bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-
- 2-Benzimidazolinone
- 1-[1-[4,4-bis(p-fluorophenyl)butyl]-4-piperidyl]- (7CI,8CI)
- 1-(1-(4,4-Bis(4-fluorophenyl)butyl)-4-piperindinyl)-1,3-dihydro-2H-benzimidazol-2-one
- 1-[1-[4,4-Bis(p-fluorophenyl)butyl]-4-piperidyl]-2-benzimidazolinone
- 1-[4,4-Bis(p-fluorophenyl)butyl]-4-(2-oxo-1-benzimidazolinyl)piperidine
- NSC 170984
- Orap
- Primozide
- R 6238
Brand:TRC
Description:Applications Pimozide is a D2 dopamine receptor antagonist that binds to the cloned 5-HT7 receptor with high affinity (1,2,3,4). Pimozide is also a Ca2+ channel antagonist. Pimozide is used as an antipsychotic.References (1) Nikonenko, I., et al.: Mol. Pharmacol., 68, 84 (2005) (2) Mariot, P., et al.: J. Biol. Chem., 277, 10824 (2002) (3) Liu, J., et al.: Br. J. Pharmacol., 126, 245 (1999) (4) Santi, C., et al.: J. Neurosci., 22, 396 (2002)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:461.55
Formula:C28H29F2N3O
Color/Form:Off-White
InChI:InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34)
InChI key:InChIKey=YVUQSNJEYSNKRX-UHFFFAOYSA-N
SMILES:O=c1[nH]c2ccccc2n1C1CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1
Technical inquiry about: Pimozide
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