Product Information
Name:Piperaquine Tetraphosphate
Controlled Product
Synonyms:
- Quinoline
- 4,4'-(1,3-propanediyldi-4,1-piperazinediyl)bis[7-chloro-
- phosphate (1:4) (9CI
- ACI)
- 4,4'-(1,3-Propanediyldi-4,1-piperazinediyl)bis[7-chloroquinoline] tetraphosphate
Brand:TRC
Description:Applications Piperaquine is a 4-aminoquinoline derivative used as an antimalarial agent. Piperaquine interferes with physiological function of the food vacuole membrane of the trophozoites leading to autophagocytosis of the parasites. It is commonly used in combination with Dihydroartemisinin (D448360) for the treatment of multi-drug resistant falciparum malaria.References Nguyen, T.M.T. et al.: Tap Chi Duoc Hoc, 57, 22 (2007); Song, J. et al.: Malaria J., 10, 231 (2011);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:927.49
Formula:C29H32Cl2N6•4H3PO4
Color/Form:Neat
InChI:InChI=1S/C29H32Cl2N6.4H3O4P/c30-22-2-4-24-26(20-22)32-8-6-28(24)36-16-12-34(13-17-36)10-1-11-35-14-18-37(19-15-35)29-7-9-33-27-21-23(31)3-5-25(27)29;4*1-5(2,3)4/h2-9,20-21H,1,10-19H2;4*(H3,1,2,3,4)
InChI key:InChIKey=UCRHFBCYFMIWHC-UHFFFAOYSA-N
SMILES:Clc1ccc2c(N3CCN(CCCN4CCN(c5ccnc6cc(Cl)ccc56)CC4)CC3)ccnc2c1
Technical inquiry about: Piperaquine Tetraphosphate
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