Pitavastatin 1-Phenylethylamide-d5

Ref. TR-P531052

Product Information

• Name: Pitavastatin 1-Phenylethylamide-d5
• Synonyms: (3R,5S,E)-7-(2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxy-N-(1-phenylethyl)hept-6-enamide-d5
• Brand: TRC
• Description: Applications Pitavastatin 1-Phenylethylamide-d5 is the isotope labelled analog of Pitavastatin 1-Phenylethylamide. Pitavastatin 1-Phenylethylamide is an impurity of Pitavastatin (P531000), which is a competitive inhibitor of HMG-CoA reductase. Antilipemic.References Aoki, T., et al.: Arzneim.-Forsch., 47, 904 (1997), Yamada, I., et al.: Xenobiotica, 33, 789 (2003), Park, S., et al.: Clin. Ther., 27, 1074 (2005),

Chemical properties

• Molecular weight: 529.656
• Formula: C₃₃D₅H₂₈FN₂O₃
• Color/Form: Neat
• InChI: InChI=1S/C33H33FN2O3/c1-21(22-7-3-2-4-8-22)35-31(39)20-27(38)19-26(37)17-18-29-32(23-13-15-25(34)16-14-23)28-9-5-6-10-30(28)36-33(29)24-11-12-24/h2-10,13-18,21,24,26-27,37-38H,11-12,19-20H2,1H3,(H,35,39)/b18-17+/t21?,26-,27-/m1/s1/i11D2,12D2,24D
• InChI key: InChIKey=JLGWZLJSEGANJP-VCRKCQIXSA-N
• SMILES: [2H]C1([2H])C([2H])([2H])C1([2H])c1nc2ccccc2c(-c2ccc(F)cc2)c1/C=C/[C@@H](O)C[C@@H](O)CC(=O)NC(C)c1ccccc1