Plumbagin-d3

CAS: 481-42-5

Ref. TR-P627002

Product Information

• Name: Plumbagin-d3
• Synonyms: 2-Methyl-5-hydroxy-1,4-naphthalenedione-d3, 2-Methyl-5-hydroxy-1,4-naphthoquinone-d3, 2-Methyljuglone-d3, 5-Hydroxy-2-methyl-1,4-naphthoquinone-d3, NSC 236613-d3, NSC 688284-d3, Plumbagine-d3, Plumbagone-d3, 1,4-Naphthalenedione, 5-hydroxy-2-methyl-, 1,4-Naphthoquinone, 5-hydroxy-2-methyl-, 2-Methyl-5-hydroxy-1,4-naphthalenedione, 2-Methyl-5-hydroxy-1,4-naphthoquinone, 2-Methyljuglone, 5-Hydroxy-2-Methylnaphthalene-1,4-Dione, 5-Hydroxy-2-methyl-1,4-naphthalenedione, 5-Hydroxy-2-methyl-1,4-naphthoquinone, NSC 236613, NSC 688284, Plumbagin from Plumbago indica, Plumbagin,95%, Plumbagine, Plumbagone

Description

Applications Plumbagin-d3 is labelled Plumbagin (P627000) which induces apoptosis in cancer cells. It also inhibits NADPH oxidase 4 in a time- and dose-dependent manner.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Klotz, L., et al.: Molecules, 19 14902 (2014); Gupta, S., et al.: Cancer Metastasis Rev., 29, 405 (2010); Schramm, A., et al.: Vascul. Pharmacol., 56, 216 (2012)

• Brand: TRC

Chemical properties

• Molecular weight: 191.2
• Formula: C₁₁H₅D₃O₃
• Color/Form: Neat
• InChI: InChI=1S/C11H8O3/c1-6-5-9(13)10-7(11(6)14)3-2-4-8(10)12/h2-5,12H,1H3/i1D3
• InChI key: InChIKey=VCMMXZQDRFWYSE-FIBGUPNXSA-N
• SMILES: [2H]C([2H])([2H])C1=CC(=O)c2c(O)cccc2C1=O