Product Information
Name:Pomalidomide-d5
Controlled Product
Synonyms:
- (S)-4-Amino-2-(2,6-dioxopiperidin-3-yl-3,4,4,5,5-d5)isoindoline-1,3-dione
Brand:TRC
Description:Applications Pomalidomide-d5 is the labeled analogue of Pomalidomide (P688200), a thalidomide derivative, a potent inhibitor of TNF-α production. It is an antiinflammatory and antitumor agent used in the treatment of multiple myeloma.References Ruchelman, A. et al.: Bioorg. Med. Chem. Lett., 23, 360 (2013); Latif, T. et al.: Exp. Hematol. Oncol., 1, 27 (2012); Man, H. et al.: Bioorg. Med. Chem. Lett., 13, 3415 (2003); Muller, G. et al.: Bioorg. Med. Chem. Lett., 9, 1625 (1999)
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Chemical properties
Molecular weight:278.27
Formula:C13D5H6N3O4
Color/Form:Neat
InChI:InChI=1S/C13H11N3O4/c14-7-3-1-2-6-10(7)13(20)16(12(6)19)8-4-5-9(17)15-11(8)18/h1-3,8H,4-5,14H2,(H,15,17,18)/t8-/m0/s1/i4D2,5D2,8D
InChI key:InChIKey=UVSMNLNDYGZFPF-XHNMXOBISA-N
SMILES:[2H]C1([2H])C(=O)NC(=O)C([2H])(N2C(=O)c3cccc(N)c3C2=O)C1([2H])[2H]
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