Polythiazide-d3

CAS: 346-18-9

Ref. TR-P689412

Product Information

• Name: Polythiazide-d3
• Synonyms: 6-Chloro-3,4-dihydro-2-(methyl-d3)-3-[[2,2,2-trifluoroethyl)thio]methyl]-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxide, (±)-Nephril-d3, 6-Chloro-3,4-dihydro-2-(methyl-d3)-7-sulfamoyl-3-(2,2,2-trifluoroethylthiomethyl)-2H-1,2,4-benzothiadiazine 1,1-Dioxide, Drenusil-d3, NSC 108161-d3, Nephril-d3, P 2525-d3, Renese-d3, (.+-.)-Nephril, (.+-.)-Polythiazide, 2-Methyl-3-(β,β,β-trifluoroethylthiomethyl)-6-chloro-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide, 6-Chloro-3,4-dihydro-2-methyl-3-[[(2,2,2-trifluoroethyl]thiomethyl]-2H-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxide, 6-Chloro-3,4-dihydro-2-methyl-3-[[2,2,2-trifluoroethyl)thio]methyl]-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 6-Chloro-3,4-dihydro-2-methyl-7-sulfamoyl-3-(2,2,2-trifluoroethylthiomethyl)-2H-1,2,4-benzothiadiazine 1,1-dioxide, Drenusil, Nsc 108161, P 2525, Politiazida, Polythiazid, Renese

Description

Applications Labelled Polythiazide. Polythiazide is a thiazide diuretic. Polythiazide is used in the treatment of hypertension as well as nephrotic syndrome, cirrhosis of the liver, and nutritional edema.
References Kaur, J. et al.: J. Ind. Med. Assoc., 48, 13, (1967); Lund-Johansen, P.: Acta Med. Scand., 187, 509 (1970); O'Brien, E.T. et al.: Br. Heart J., 34, 1042 (1972);

• Brand: TRC

Chemical properties

• Molecular weight: 442.9
• Formula: C₁₁H₁₀D₃ClF₃N₃O₄S₃
• Color/Form: Neat
• InChI: InChI=1S/C11H13ClF3N3O4S3/c1-18-10(4-23-5-11(13,14)15)17-7-2-6(12)8(24(16,19)20)3-9(7)25(18,21)22/h2-3,10,17H,4-5H2,1H3,(H2,16,19,20)/i1D3
• InChI key: InChIKey=CYLWJCABXYDINA-FIBGUPNXSA-N
• SMILES: [2H]C([2H])([2H])N1C(CSCC(F)(F)F)Nc2cc(Cl)c(S(N)(=O)=O)cc2S1(=O)=O