Polyphyllin II

CAS: 76296-72-5

Ref. TR-P689460

Product Information

• Name: Polyphyllin II
• Synonyms: (3ß,25R)-Spirost-5-en-3-yl O-a-L-arabinofuranosyl-(1?4)-O-[6-deoxy-a-L-mannopyranosyl-(1?3)]-ß-D-glucopyranoside (ACI), Polyphyllin D, (3β,25R)-Spirost-5-en-3-yl O-α-<span class="text-smallcaps">L</smallcap>-arabinofuranosyl-(1→4)-O-[6-deoxy-α-<smallcap>L</smallcap>-mannopyranosyl-(1→3)]-β-<smallcap>D</span>-glucopyranoside, Chonglou Saponin II, β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl O-α-<smallcap>L</smallcap>-arabinofuranosyl-(1→4)-O-[6-deoxy-α-<smallcap>L</span>-mannopyranosyl-(1→3)]-, β-D-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl O-α-L-arabinofuranosyl-(1→4)-O-[6-deoxy-α-L-mannopyranosyl-(1→3)]-, (3β,25R)-Spirost-5-en-3-yl O-α-L-arabinofuranosyl-(1→4)-O-[6-deoxy-α-L-mannopyranosyl-(1→3)]-β-D-glucopyranoside

Description

Applications Polyphylin II is a natural saponin extracted from the plant, Paris polyphylla, and displays antiproliferative activity in vivo.
References Ma, D. et al.: J. Int Med. Res., 37, 631 (2009); Yin, X. et al.: Biomed. Chrom., 27, 343 (2013);

• Brand: TRC

Chemical properties

• Molecular weight: 855.02
• Formula: C₄₄H₇₀O₁₆
• Color/Form: Neat
• InChI: InChI=1S/C44H70O16/c1-19-8-13-44(53-18-19)20(2)30-27(60-44)15-26-24-7-6-22-14-23(9-11-42(22,4)25(24)10-12-43(26,30)5)55-41-36(52)38(59-39-35(51)33(49)31(47)21(3)54-39)37(29(17-46)57-41)58-40-34(50)32(48)28(16-45)56-40/h6,19-21,23-41,45-52H,7-18H2,1-5H3
• InChI key: InChIKey=QSVBUQTYFQFEHC-NTRKLXJCSA-N
• SMILES: C[C@H]1C[C@@H]2[C@@H]3C[C@@H](F)C4=CC(=O)C=C[C@]4(C)[C@]3(F)[C@@H](O)C[C@]2(C)[C@]1(O)C(=O)O