Polyhyllin VI

CAS: 55916-51-3

Ref. TR-P689480

Product Information

• Name: Polyhyllin VI
• Synonyms: (3ß,25R)-17-hydroxyspirost-5-en-3-yl 2-O-(6-deoxy-a-L-mannopyranosyl)-ß-D-Glucopyranoside, 17-Hydroxyparis V, Paris VI, Paris Saponin VI, Pennogenin, 3-O-a-L-rhamnopyranosyl-(1?2)-ß-D-glucopyranoside, Olygonatoside B3 ,Saponin Tb, (3β,25R)-17-Hydroxyspirost-5-en-3-yl 2-O-(6-deoxy-α-<span class="text-smallcaps">L</smallcap>-mannopyranosyl)-β-<smallcap>D</span>-glucopyranoside, Paris saponin VI, ParisVI, Pennogenin 3-O-a-L-rhamnopyranosyl-(1® 2)-b-D-glucopyranoside, Pennogenin 3-O-α-<span class="text-smallcaps">L</smallcap>-rhamnopyranosyl-(1→2)-β-<smallcap>D</span>-glucopyranoside, Pennogenin-3-O-α-<span class="text-smallcaps">L</smallcap>-rhamnopyranosyl(1→2)-β-<smallcap>D</span>-glucoside, Polygonatoside B3, Polygonatoside B³, Polyphyllin VI, Saponin Tb, β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,25R)-17-hydroxyspirost-5-en-3-yl 2-O-(6-deoxy-α-<smallcap>L</span>-mannopyranosyl)-, Pennogenin 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside, β-D-Glucopyranoside, (3β,25R)-17-hydroxyspirost-5-en-3-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-, (3β,25R)-17-Hydroxyspirost-5-en-3-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside

Description

Applications Polyhyllin VI is a natural saponin extracted from the plant, Rhizoma Paridis, and displays anti-proliferative activity in vivo. Used in the treatment of HepG2 cells for tumor mitigation.
References Ma, D. et al.: J. Int Med. Res., 37, 631 (2009); Yin, X. et al.: Biomed. Chrom., 27, 343 (2013); Jiang, H. et al.: Mol. Med. Rep., 9, 2265 (2014); Cheng, Z. et al.: J. Ethnopharmacol., 120, 129 (2008);

• Brand: TRC

Chemical properties

• Molecular weight: 738.9
• Formula: C₃₉H₆₂O₁₃
• Color/Form: Neat
• InChI: InChI=1S/C8H7NO3/c10-5-9-7-3-1-6(2-4-7)8(11)12/h1-5H,(H,9,10)(H,11,12)
• InChI key: InChIKey=ZBCGPWAZRMLTKF-UHFFFAOYSA-N
• SMILES: O=CNc1ccc(C(=O)O)cc1