(R)-Pramipexole Dihydrochloride

CAS: 104632-27-1

Ref. TR-P700745

Product Information

• Name: (R)-Pramipexole Dihydrochloride
• Synonyms: (6R)-4,5,6,7-Tetrahydro-N6-propyl-2,6-benzothiazolediamine dihydrochloride, (R)-4,5,6,7-Tetrahydro-N6-propyl-2,6-benzothiazolediamine dihydrochloride, (R)-4,5,6,7-Tetrahydro-6-(propylamino)-benzothiazole-2-amine dihydrochloride, Dexpramipexole dihydrochloride, KNS 760704, SND 919CL2X, Pramipexole Imp. D (EP) as Dihydrochloride

Description

Impurity Pramipexole EP Impurity D; Pramipexole BP Impurity D; Pramipexole USP Related Compound D
Applications (R)-Pramipexole Dihydrochloride (Pramipexole EP Impurity D; Pramipexole BP Impurity D; Pramipexole USP Related Compound D) is the opposite enantiomer of Pramipexole (P700755), a dopamine-D2-receptor agonist. Dexpramipexole is a low-molecular-weight, water-soluble, orally bioavailable, renally excreted compound with linear pharmacokinetics.
References Mierau, J., et al.: J. Med. Chem., 30, 494 (1987), Schilling, J.C., et al.: Clin. Pharmacol. Ther., 51, 541 (1992), Kieburtz, K., et al.: J. Am. Med. Assoc., 278, 125 (1997)

• Brand: TRC

Chemical properties

• Molecular weight: 284.25
• Formula: C₁₀H₁₇N₃SClH
• Color/Form: Neat
• InChI: /h7,12H,2-6H2,1H3,(H2,11,13), , 2*1H/t7-, InChI=1S/C10H17N3S.2ClH/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8, /m1../s1,
• InChI key: InChIKey=QMNWXHSYPXQFSK-XCUBXKJBSA-N
• SMILES: CCCN[C@@H]1CCc2nc(N)sc2C1.Cl.Cl