Pregna-​4,​9(11)​-​diene-​3,​20-​dione (90%)

CAS: 17652-16-3

Ref. TR-P704970

Product Information

• Name: Pregna-​4,​9(11)​-​diene-​3,​20-​dione (90%)
• Synonyms: Pregna-4,9(11)-diene-3,20-dione, 9-Dehydroprogesterone, ?9(11)-Progesterone, Progesterone Imp. K (EP)

Description

Applications Pregna-​4,​9(11)​-​diene-​3,​20-​dione is a Progesterone (P755900) impurity, a steroid hormone produced by the corpus luteum. Induces maturation and secretory activity of the uterine endothelium; suppresses ovulation. Progesterone is implicated in the etiology of breast cancer.
References Thomas, P. et al.: Endocrinol., 148, 705 (2007); Anderson, E., et al.: Breast Cancer Res., 4, 197 (2002), Lanari, C., et al.: Breast Cancer Res., 4, 240 (2002), Albrecht, E.D., et al.: Front. Biosci., 8, 416 (2003), Qiu, M., et al.: J. Steroid Biochem. Mol. Biol., 85, 147 (2003),

• Brand: TRC

Chemical properties

• Molecular weight: 312.45
• Formula: C₂₁H₂₈O₂
• Purity: 90%
• Color/Form: Neat
• InChI: InChI=1S/C21H28O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h9,12,16-18H,4-8,10-11H2,1-3H3/t16-,17+,18-,20-,21+/m0/s1
• InChI key: InChIKey=LCXMRSLFWMMCAS-WRJHFWDFSA-N
• SMILES: CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)C3=CC[C@]12C