5α-Pregnan-3β-ol-20-one 3β-Acetate

CAS: 906-83-2

Ref. TR-P711315

Product Information

• Name: 5α-Pregnan-3β-ol-20-one 3β-Acetate
• Synonyms: [(3S,5S,8R,9S,13S,14S,17S)-17-acetyl-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate, (3Beta,5Alpha)-20-Oxopregnan-3-Yl Acetate, (3Beta,5Alpha,17Alpha)-20-Oxopregnan-3-Yl Acetate, Allopregnan-3β-ol-20-one acetate

Description

Applications 5α-Pregnan-3β-ol-20-one 3β-Acetate is a derivative of Pregnenolone (P712200); a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens. As such it is a prohormone. Pregnenolone is a GABAA antagonist and increases neurogenesis in the hippocampus. It is a modulator of cytochrome P 450-3A.
References Bjondahl, K., et al.: Med. Biol., 54, 454 (1976); Geick, A., et al.: J. Biol. Chem., 276, 14581 (2001); Johnson, D., et al.: Toxicol. Sci., 66, 16 (2002); Abe, C., et al.: Lipids, 42, 637 (2007)

• Brand: TRC

Chemical properties

• Molecular weight: 360.53
• Formula: C₂₃H₃₆O₃
• Color/Form: Neat
• InChI: InChI=1S/C23H36O3/c1-14(24)19-7-8-20-18-6-5-16-13-17(26-15(2)25)9-11-22(16,3)21(18)10-12-23(19,20)4/h16-21H,5-13H2,1-4H3/t16-,17-,18-,19+,20-,21-,22?,23+/m0/s1
• InChI key: InChIKey=GFHOQCXDABGYAL-MQEXSEHRSA-N
• SMILES: CC(=O)O[C@H]1CCC2(C)[C@@H](CC[C@@H]3[C@@H]2CC[C@]2(C)[C@@H](C(C)=O)CC[C@@H]32)C1