Pregnenolone-d6 Major

CAS: 145-13-1

Ref. TR-P712203

Product Information

• Name: Pregnenolone-d6 Major
• Synonyms: (3ß)-3-Hydroxy-pregn-5-en-20-one-d6, (3ß)-3-Hydroxypregn-5-en-20-one-d6, 5-Pregnenolone-d6, Arthenolone-d6, Bina-Skin-d6, Enelone-d6, NSC 1616-d6, Pregnolon-d6, Prenolon-d6, Regnosone-d6, Skinostelon-d6, (3β)-3-Hydroxypregn-5-en-20-one, 17β-[1-Ketoethyl]-Δ5-androsten-3β-ol, 17β-[1-Ketoethyl]-Δ⁵-androsten-3β-ol, 3β-Hydroxy-5-en-20-one, 3β-Hydroxy-5-pregnene-20-one, 3β-Hydroxy-Δ5-pregnen-20-one, 3β-Hydroxy-Δ⁵-pregnen-20-one, 3β-Hydroxypregn-5-en-20-one, 5-Pregnenolone, Arthenolone, Bina-Skin, Enelone, Natolone, Nsc 1616, Nsc 18158, Pregn-5-en-20-one, 3β-hydroxy-, Pregn-5-en-3β-ol-20-one, Pregn-5-ene-3β-ol-20-one, Pregnelon, Pregnenolon, Pregnenolona, Pregnenolone, Pregnenolone (progesterone precursor), Pregnetan, Pregneton, Pregnolon, Prenolon, Regnosone, Skinostelon, Δ5-Pregnen-3β-ol-20-one, Δ5-Pregnene-3β-ol-20-one, Δ5-Pregnenolone, Δ⁵-Pregnen-3β-ol-20-one, Δ⁵-Pregnene-3β-ol-20-one, Δ⁵-Pregnenolone

Description

Applications Pregnenolone-d6 is the labeled analogue of Pregnenolone (P712200), a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens. As such it is a prohormone. Pregnenolone is a GABAA antagonist and increases neurogenesis in the hippocampus. It is a modulator of cytochrome P 450-3A.
References Bjondahl, K., et al.: Med. Biol., 54, 454 (1976); Geick, A., et al.: J. Biol. Chem., 276, 14581 (2001); Johnson, D., et al.: Toxicol. Sci., 66, 16 (2002); Abe, C., et al.: Lipids, 42, 637 (2007)

• Brand: TRC

Chemical properties

• Molecular weight: 322.51
• Formula: C₂₁D₆H₂₆O₂
• Color/Form: Neat
• InChI: InChI=1S/C21H32O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h4,15-19,23H,5-12H2,1-3H3/t15-,16-,17+,18-,19-,20-,21+/m0/s1/i4D,8D2,12D2,15D
• InChI key: InChIKey=ORNBQBCIOKFOEO-NKURGQCQSA-N
• SMILES: [2H]C1=C2C([2H])([2H])[C@@]([2H])(O)C([2H])([2H])C[C@]2(C)[C@H]2CC[C@]3(C)[C@@H](C(C)=O)CC[C@H]3[C@@H]2C1