δ4-Pregnen-20α-ol-3-one-(d4 major)

CAS: 145-14-2

Ref. TR-P712217

Product Information

• Name: δ4-Pregnen-20α-ol-3-one-(d4 major)
• Synonyms: 20(S)-Hydroxyprogesterone-d4, 20-Hydroxypregn-4-en-3-one-d4, 20α-Dihydroprogesterone-d4, 20α-Hydroxy-4-pregnen-3-one-d4, 20α-Hydroxy-Δ4-pregnen-3-one-d4, 20α-Hydroxydihydroprogesterone-d4, 20α-Hydroxypregn-4-en-3-one-d4, 20α-Hydroxyprogesterone-d4, 20α-Progerol-d4, 4-Pregnen-3-one-20α-ol-d4, NSC 68630-d4, Pregn-4-en-20α-ol-3-one-d4, Pregn-4-ene-20α-ol-3-one-d4, Progesterol-20α-d4
• Brand: TRC
• Description: Applications Labelled Δ4-Pregnen-20α-ol-3-one (P712215). Δ4-Pregnen-20α-ol-3-one is the main metabolite of Progesterone (P755900). Studies shows regulation of estrogen receptor levels in breast cancer by Δ4-Pregnen-20α-ol-3-one and other progesterone metabolites.References Zhang, L. et al.: Yaoz. Xueb., 39, 613 (2004); Pawlak, K.J. et al.: J. Steroid. Biochem. Mol. Biol., 107, 172 (2007)

Chemical properties

• Molecular weight: 320.5
• Formula: C₂₁H₂₈D₄O₂
• Color/Form: Neat
• InChI: InChI=1S/C21H32O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12-13,16-19,22H,4-11H2,1-3H3/t13?,16-,17-,18+,19+,20-,21-/m0/s1/i4D,8D2,12D/t4-,13?,16+,17+,18-,19-,20+,21+/m1
• InChI key: InChIKey=RWBRUCCWZPSBFC-SFHLGCGRSA-N
• SMILES: [2H]C1=C2[C@H]([2H])C[C@@H]3[C@@H](CC[C@@]4(C)[C@H](C(C)O)CC[C@H]34)[C@@]2(C)CC([2H])([2H])C1=O