Delta4-Pregnen-20Alpha-ol-3-one-(d4 major)

CAS: 145-14-2

Ref. TR-P712217

Product Information

• Name: Delta4-Pregnen-20Alpha-ol-3-one-(d4 major)
• Synonyms: 20(S)-Hydroxyprogesterone-d4, 20-Hydroxypregn-4-en-3-one-d4, 20a-Dihydroprogesterone-d4, 20a-Hydroxy-4-pregnen-3-one-d4, 20a-Hydroxy-?4-pregnen-3-one-d4, 20a-Hydroxydihydroprogesterone-d4, 20a-Hydroxypregn-4-en-3-one-d4, 20a-Hydroxyprogesterone-d4, 20a-Progerol-d4, 4-Pregnen-3-one-20a-ol-d4, NSC 68630-d4, Pregn-4-en-20a-ol-3-one-d4, Pregn-4-ene-20a-ol-3-one-d4, Progesterol-20a-d4, ?4-Pregnene-20a-ol-3-one-d4, (20R)-20-hydroxypregn-4-en-3-one, (20S)-20-Hydroxypregn-4-en-3-on, (20S)-20-Hydroxypregn-4-en-3-one, (20S)-20-hidroxipregn-4-en-3-ona, (20S)-20-hydroxypregn-4-ene-3-one, (8S,9S,10R,13S,14S,17S)-17-(1-hydroxyethyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one, (8xi,9xi,14xi,17xi,20S)-20-hydroxypregn-4-en-3-one, 20(S)-Hydroxyprogesterone, 20-Hydroxypregn-4-En-3-One, 20-alpha-Dihydroprogesterone, 20-alpha-Hydroxydihydroprogesterone, 20-alpha-Hydroxyprogesterone, 20-alpha-Progerol, 20alpha-Dihydroprogesterone, 20alpha-Dihydroprognenolone, 20alpha-Hydroxydihydroprogesterone, 20alpha-Hydroxypreg-4-en-3-one, 20alpha-Hydroxypregnen-2-one, 20alpha-Progerol, 20α-Dihydroprogesterone, 20α-Hydroxy-4-pregnen-3-one, 20α-Hydroxy-Δ4-pregnen-3-one, 20α-Hydroxy-Δ⁴-pregnen-3-one, 20α-Hydroxydihydroprogesterone, 20α-Hydroxypregn-4-en-3-one, 20α-Hydroxyprogesterone, 20α-Progerol, 4-Pregnen-3-one-20α-ol, Brn 2220567, Dihydrogesterone, Dihydroprogesterone, Nsc 68630, Pregn-4-en-20α-ol-3-one, Pregn-4-en-3-one, 20-alpha-hydroxy-, Pregn-4-en-3-one, 20-hydroxy-, (20S)-, Pregn-4-en-3-one, 20-hydroxy-, (20S)- (9CI), Pregn-4-en-3-one, 20alpha-hydroxy- (8CI), Pregn-4-en-3-one, 20α-hydroxy-, Pregn-4-ene-20α-ol-3-one, Progesterol-20-alpha, Progesterol-20α, Δ4-Pregnen-20α-ol-3-one, Δ4-Pregnene-20α-ol-3-one, Δ⁴-Pregnen-20α-ol-3-one, Δ⁴-Pregnene-20α-ol-3-one, 4-08-00-01018 (Beilstein Handbook Reference)

Description

Applications Labelled Δ4-Pregnen-20α-ol-3-one (P712215). Δ4-Pregnen-20α-ol-3-one is the main metabolite of Progesterone (P755900). Studies shows regulation of estrogen receptor levels in breast cancer by Δ4-Pregnen-20α-ol-3-one and other progesterone metabolites.
References Zhang, L. et al.: Yaoz. Xueb., 39, 613 (2004); Pawlak, K.J. et al.: J. Steroid. Biochem. Mol. Biol., 107, 172 (2007);

• Brand: TRC

Chemical properties

• Molecular weight: 320.5
• Formula: C₂₁H₂₈D₄O₂
• Color/Form: Neat
• InChI: InChI=1S/C21H32O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12-13,16-19,22H,4-11H2,1-3H3/t13?,16-,17-,18+,19+,20-,21-/m0/s1/i4D,8D2,12D/t4-,13?,16+,17+,18-,19-,20+,21+/m1
• InChI key: InChIKey=RWBRUCCWZPSBFC-SFHLGCGRSA-N
• SMILES: [2H]C1=C2[C@H]([2H])C[C@@H]3[C@@H](CC[C@@]4(C)[C@H](C(C)O)CC[C@H]34)[C@@]2(C)CC([2H])([2H])C1=O