8-Prenylquercetin

CAS: 143724-75-8

Ref. TR-P712910

Product Information

• Name: 8-Prenylquercetin
• Synonyms: 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-8-(3-methylbut-2-enyl)chromen-4-one

Description

Applications 8-Prenylquercetin is a natural product derived from Quercetin (Q509500). Quercetin is a flavonoid with anticancer activity. It is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle.
References Graziani, Y. et al.: J. Biochem., 135, 583 (1983); Levy, J. et al.: Biochem. Biophys. Res. Comm., 123, 1227 (1984); Wei, Y.Q. et al.: Cancer Res., 54, 4952 (1994)

• Brand: TRC

Chemical properties

• Molecular weight: 370.353
• Formula: C₂₀H₁₈O₇
• Color/Form: Neat
• InChI: InChI=1S/C20H18O7/c1-9(2)3-5-11-13(22)8-15(24)16-17(25)18(26)19(27-20(11)16)10-4-6-12(21)14(23)7-10/h3-4,6-8,21-24,26H,5H2,1-2H3
• InChI key: InChIKey=ZHTTWVRMGWQEOH-UHFFFAOYSA-N
• SMILES: CC(C)=CCc1c(O)cc(O)c2c(=O)c(O)c(-c3ccc(O)c(O)c3)oc12