Proligestone

CAS: 23873-85-0

Ref. TR-P755960

Product Information

• Name: Proligestone
• Synonyms: 14,17-[Propylidenebis(oxy)]-pregn-4-ene-3,20-dione, 14α,17α-Propylidenedioxypregn-4-ene-3,20-dione, (1R,4aR,4bR,10aR,10bS,12aS)-1-acetyl-3-ethyl-10a,12a-dimethyl-1,5,6,9,10,10a,10b,11,12,12a-decahydro-1,4a-ethanophenanthro[1,2-d][1,3]dioxin-8(4bH)-one, 1,4a-Ethano-4aH-phenanthro[1,2-d][1,3]dioxin, pregn-4-ene-3,20-dione deriv., 14,17-Dihydroxypregn-4-ene-3,20-dione, cyclic acetal with propionaldehyde, 14,17-[Propylidenebis(oxy)]pregn-4-ene-3,20-dione, Pregn-4-ene-3,20-dione, 14,17-[propylidenebis(oxy)]-, Pregn-4-ene-3,20-dione, 14,17-dihydroxy-, cyclic acetal with propionaldehyde, Proligestona, Proligestona [INN-Spanish], Proligestone [INN:BAN], Proligestonum, Proligestonum [INN-Latin], Unii-55772Lj01V

Description

Applications Proligestone is a derivative of 17α-Hydroxy Progesterone (H952330), which is a metabolite of Progesterone (P755900), a steroid hormone produced by the corpus luteum. Proligestone maintains the ability to affect the hypothalmic-pituitary-adrenocortical axis and glucose homeostasis.
References Pfiffner, N., et al.: J. Biol. Chem., 132, 459 (1940); Florey, K., et al.: Anal. Profiles Drug Subs.,4, 209 (1975); Albrecht, E.D., et al.: Front. Biosci., 8, 416 (2003); Qiu, M., et al.: J. Steroid Biochem. Mol. Biol., 85, 147 (2003); Zeinalov, O. et al.: Pharm. Chem. J., 46, 203 (2012); Selman, P. et al.: J. Reprod. Fertil. Suppl. 52, 345 (1997);

• Brand: TRC

Chemical properties

• Molecular weight: 386.52
• Formula: C₂₄H₃₄O₄
• Color/Form: Neat
• InChI: InChI=1S/C24H34O4/c1-5-20-27-23(15(2)25)12-13-24(28-20)19-7-6-16-14-17(26)8-10-21(16,3)18(19)9-11-22(23,24)4/h14,18-20H,5-13H2,1-4H3/t18-,19+,20?,21-,22+,23-,24+/m0/s1