Promazine Sulfoxide

CAS: 146-21-4

Ref. TR-P756310

Product Information

• Name: Promazine Sulfoxide
• Synonyms: Promazine Imp. A (EP), 3-(10H-Phenothiazin-10-yl)-N,N-dimethylpropan-1-amine S-Oxide, Promazine Sulphoxide, Promazine Hydrochloride Impurity A, Promazine Impurity A,3-(10H-Phenothiazin-10-yl)-N,N-dimethylpropan-1-amine S-Oxide (Promazine Sulphoxide), Promazine Hydrochloride Imp. A (EP), Phenothiazine,10-[3-(dimethylamino)propyl]-, 5-oxide (6CI,7CI,8CI), Promazine 5-oxide, Promazine S-oxide, Promazine sulfoxide, Propazin sulfoxide, Propazinesulfoxide, Skf 5418A

Description

Applications Promazine Sulfoxide is a metabolite of Chlorpromazine (C424750) and an impurity of Promazine (P756300). Both Chlorpromazine and Promazine are antipsychotic drugs.
References Zhang, S., et al.: Fenxi Ceshi Xuebao, 30, 1088 (2011); Anden, N.-E., et al.: Eur. J. Pharmacol., 11, 303 (1970), Curzon, G., et al.: Trends Pharmacol. Sci., 11, 61 (1990); Banci, L., et al.: Biochemistry, 38, 3205 (1999), Lawal, O., et al.: Food Chemi., 87, 205 (2004); Shleev, S., et al.: Bioorg. Chem., 35, 35 (2007);

• Brand: TRC

Chemical properties

• Molecular weight: 300.42
• Formula: C₁₇H₂₀N₂OS
• Color/Form: Light Yellow
• InChI: InChI=1S/C17H20N2OS/c1-18(2)12-7-13-19-14-8-3-5-10-16(14)21(20)17-11-6-4-9-15(17)19/h3-6,8-11H,7,12-13H2,1-2H3
• InChI key: InChIKey=KSHDHDWHIWBNHA-UHFFFAOYSA-N
• SMILES: CN(C)CCCN1c2ccccc2S(=O)c2ccccc21