4-Propionamidophenol (Acetaminophen Impurity B)

CAS: 1693-37-4

Ref. TR-P783500

Product Information

• Name: 4-Propionamidophenol (Acetaminophen Impurity B)
• Synonyms: Paracetamol Imp. B (EP), Acetaminophen USP Related Compound B, Acetaminophen USP RC B, N-(4-Hydroxyphenyl)-propanamide, N-Propionyl-4-aminophenol, Acetaminophen Related Compound B, Paracetamol Impurity B, 4'-Hydroxypropionanilid, 4-(Propionylamino)phenol, 4-Propionamidophenol, 4′-Hydroxypropionanilide, N-(4-Hydroxyphenyl)propionamide, N-(4-hydroxyphenyl)propanamide, N-(p-Hydroxyphenyl)propionamide, Parapropamol [INN:DCF], Parapropamolo, Parapropamolo [DCIT], Parapropamolum, Parapropamolum [INN-Latin], Parapropanol, Propanamide, N-(4-hydroxyphenyl)-, Propionanilide, 4′-hydroxy-, Solvodol, Unii-I729P6N0P7, p-Hydroxypropionanilide, p-Propionamidophenol

Description

Impurity Paracetamol EP Impurity B, Acetaminophen Related Compound B (USP)
Applications 4-Propionamidophenol (Acetaminophen Impurity B) is an impurity of Acetaminophen (A161220) (1). Acetaminophen is an analgesic and antipyretic agent and used as a pain reliever to treat headache, muscle aches, and arthritis (2,3).
References (1) Hajduk, P., et al.: Science, 278, 497 (2) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(3) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974)

• Brand: TRC

Chemical properties

• Molecular weight: 165.19
• Formula: C₉H₁₁NO₂
• Color/Form: White
• InChI: InChI=1S/C9H11NO2/c1-2-9(12)10-7-3-5-8(11)6-4-7/h3-6,11H,2H2,1H3,(H,10,12)
• InChI key: InChIKey=SSMYTAQHMUHRSK-UHFFFAOYSA-N
• SMILES: CCC(=O)Nc1ccc(O)cc1