Dextropropoxyphene

CAS: 469-62-5

Ref. TR-P831505

Product Information

• Name: Dextropropoxyphene
• Synonyms: (2S,3R)-4-(Dimethylamino)-3-methyl-1,2-diphenyl-2-butanol propionate (ester), (+)-4-(Dimethylamino)-3-methyl-1,2-diphenyl-2-butanol propionate, (+)-Propoxyphene, Algafan, Depromic, Dextropropoxyphen, Propoxyphene, d-Propoxyphene, (alphaS)-alpha-[(1R)-2-(Dimethylamino)-1-methylethyl]-alpha-phenylbenzeneethanol 1-propanoate, (alphaS)-alpha-[(1R)-2-(Dimethylamino)-1-methylethyl]-alpha-phenylbenzeneethanol propanoate (ester), [S-(R*,S*)]-alpha-[(1R)-2-(Dimethylamino)-1-methylethyl]-alpha-phenylbenzeneethanol propanoate (ester), alpha-(+)-4-(Dimethylamino)-1,2-diphenyl-3-methyl-2-butanol propionate, alpha-d-4-(Dimethylamino)-3-methyl-1,2-diphenyl-2-(propionyloxy)butane, (+)-(1-Benzyl-3-dimethylamino-2-methyl-1-phenylpropyl)propionate, 2-Butanol, 4-(dimethylamino)-3-methyl-1,2-diphenyl-, propionate (ester), (2S,3R)-, Benzeneethanol, α-[(1R)-2-(dimethylamino)-1-methylethyl]-α-phenyl-, 1-propanoate, (αS)-, Benzeneethanol, α-[2-(dimethylamino)-1-methylethyl]-α-phenyl-, propanoate (ester), [S-(R*,S*)]-, Dextropropoxifeno, α-(+)-4-(Dimethylamino)-1,2-diphenyl-3-methyl-2-butanol propionate, α-d-4-(Dimethylamino)-3-methyl-1,2-diphenyl-2-(propionyloxy)butane

Description

Applications Propoxyphene, is a controlled substance (opiate). Analgesic (narcotic). The α-dl-and d-diastereoisomers possess marked analgesic activity in contrast to the β-diastereoisomers which are substantially inactive.
References Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971), McEwan, B., et al.: Anal. Profiles Drug Subs., 1, 301 (1972)

• Brand: TRC

Chemical properties

• Molecular weight: 339.47
• Formula: C₂₂H₂₉NO₂
• Color/Form: White
• InChI: InChI=1S/C22H29NO2/c1-5-21(24)25-22(18(2)17-23(3)4,20-14-10-7-11-15-20)16-19-12-8-6-9-13-19/h6-15,18H,5,16-17H2,1-4H3/t18-,22+/m1/s1
• InChI key: InChIKey=XLMALTXPSGQGBX-ZZWBGTBQSA-N
• SMILES: CCC(=O)OC(Cc1ccccc1)(c1ccccc1)[C@H](C)CN(C)C