Prostaglandin F2α Tromethamine Salt

CAS: 38562-01-5

Ref. TR-P838625

Product Information

• Name: Prostaglandin F2α Tromethamine Salt
• Synonyms: Dinoprost trometamol, Trometamol (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-(3S)-3-hydroxyoct-1-enyl]cyclopentyl]hept-5-enoate, PGF2a, (5E,9alpha,11alpha,13E,15S)-9,11,15-trihydroxyprosta-5,13-dien-1-oic acid-2-amino-2-(hydroxymethyl)propane-1,3-diol (1:1), (5Z,9alpha,11alpha,13E,15S)-9,11,15-trihydroxyprosta-5,13-dien-1-oic acid, (5Z,9alpha,11alpha,13E,15S)-9,11,15-trihydroxyprosta-5,13-dien-1-oic acid-2-amino-2-(hydroxymethyl)propane-1,3-diol (1:1), 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, (5Z,9α,11α,13E,15S)-9,11,15-trihydroxyprosta-5,13-dien-1-oate (salt), Dinolytic, Dinoprost Trometamol, Dinoprost Tromethamine, Dinoprost, Sel De Trometamol, Dinoprost, Trometamol Salt, Dinoprost, Trometamolsalz, Dinoprosta,Sal De Trometamol, Dinorprost tromethamine, Enzaprost T, Lutalyse, Lutalyze, Minprostin F2α, Minprostin F_2α, Nsc 196515, PGF2α THAM, PGF2α THAM salt, PGF2α Tris salt, PGF2α tromethamine, PGF2α tromethamine salt, PGF_2α THAM, PGF_2α THAM salt, PGF_2α Tris salt, PGF_2α tromethamine, PGF_2α tromethamine salt, Pronalgon F, Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, (5Z,9α,11α,13E,15S)-, compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1), Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, (5Z,9α,11α,13E,15S)-, compound with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1), Prostaglandin F2a tromethamine salt, Prostaglandin F2alpha tris salt, Prostaglandin F2α THAM salt, Prostaglandin F2α tris(hydroxymethyl)aminomethane, Prostaglandin F2α tris(hydroxymethyl)aminomethane salt, Prostaglandin F2α tromethamine, Prostaglandin F2α-tham, Prostaglandin F₂α-tham, Prostaglandin F_2a tromethamine salt, Prostaglandin F_2α THAM salt, Prostaglandin F_2α tris(hydroxymethyl)aminomethane, Prostaglandin F_2α tris(hydroxymethyl)aminomethane salt, Prostaglandin F_2α tromethamine, THAM PGF2α, THAM PGF_2α, Tromethamine prostaglandin F2α, Tromethamine prostaglandin F_2α, U 14583E, U 14585, prostaglandin F2-alpha, trometamol salt, prostaglandin F2A gamma-irradiated, prostaglandin F2A tris

Description

Stability Hygroscopic
Applications One of the most biologically studied of the primary prostaglandins. Closely related to Prostaglandin E2 (PGE2) in that both prostaglandins are biosynthesized from the same precursors and that PGF2 is the synthetic reduction product of PGE2. Phospholipase A2 (PLA2) is a key enzyme for biosynthesis of PGF2α. Oxytocic; abortifacient.
References Granstrom, S., et al.: J. Biol. Chem., 246, 5254 (1971), Kubota, Y., et al.: Eur. J. Pharmacol., 467, 191 (2003), Crowell, J., et al.: Toxicol. Sci., 82, 614 (20040,

• Brand: TRC

Chemical properties

• Molecular weight: 475.62
• Formula: C₂₀H₃₄O₅·C₄H₁₁NO₃
• Color/Form: Neat
• InChI: InChI=1S/C20H34O5.C4H11NO3/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25;5-4(1-6,2-7)3-8/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25);6-8H,1-3,5H2/b7-4-,13-12+;/t15-,16+,17+,18-,19+;/m0./s1
• InChI key: InChIKey=IYGXEHDCSOYNKY-RZHHZEQLSA-N
• SMILES: CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@@H]1C/C=C\CCCC(=O)O.NC(CO)(CO)CO