Product Information
Name:PRT 060318
Controlled Product
Synonyms:
- 2-[[(1R,2S)-2-Aminocyclohexyl]amino]-4-[(3-methylphenyl)amino]-5-pyrimidinecarboxamide
- P 142-76
- PRT 318
Brand:TRC
Description:Applications PRT 060318 is a novel selective inhibitor of the tyrosine kinase Syk. PRT 060318 may be used in Heparin-Induced Thrombocytopenia (HIT) treatment. HIT is a major cause of morbidity and mortality.References Reilly, M.P., et al.: Blood., 117, 2241 (2011)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:340.42
Formula:C18H24N6O
Color/Form:Neat
InChI:InChI=1S/C18H24N6O/c1-11-5-4-6-12(9-11)22-17-13(16(20)25)10-21-18(24-17)23-15-8-3-2-7-14(15)19/h4-6,9-10,14-15H,2-3,7-8,19H2,1H3,(H2,20,25)(H2,21,22,23,24)/t14-,15+/m0/s1
InChI key:InChIKey=NZNTWOVDIXCHHS-LSDHHAIUSA-N
SMILES:Cc1cccc(N=c2[nH]c(N[C@@H]3CCCC[C@@H]3N)ncc2C(=N)O)c1
Technical inquiry about: PRT 060318
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