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2-Pyrazinecarbonyl Chloride

CAS:

Ref. TR-P840805

250mg
1,022.00€
2-Pyrazinecarbonyl Chloride
TRC

Product Information

Name:2-Pyrazinecarbonyl Chloride
Controlled Product
Synonyms:
  • Pyrazine-2-carboxylic Acid Chloride
  • Pyrazinoic Acid Chloride
  • Pyrazinoyl Chloride
  • Pyrazinecarbonyl Chloride
Brand:TRC
Description:Applications 2-Pyrazinecarbonyl Chloride is an intermediate used in the synthesis of (S)-N-[1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2yl]pyrazine-2-carboxamide (H805105), which is an impurity of bortezomib (B675700), which is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.
Notice:Our products are intended for lab use only. For any other use, please contact us.

Chemical properties

Molecular weight:142.543
Formula:C5H3ClN2O
Color/Form:Neat
InChI:InChI=1S/C5H3ClN2O/c6-5(9)4-3-7-1-2-8-4/h1-3H
InChI key:InChIKey=TXJKATOSKLUITR-UHFFFAOYSA-N
SMILES:O=C(Cl)c1cnccn1

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