1-Pyrrolidinecarbodithioic Acid Ammonium Salt

CAS: 5108-96-3

Ref. TR-P997985

Product Information

• Name: 1-Pyrrolidinecarbodithioic Acid Ammonium Salt
• Synonyms: APDC, Ammonium 1-pyrrolidinecarbodithioate,1-Pyrrolidinecarbodithioic acid, ammonium salt (8CI,9CI), 1-Pyrrolidinedithiocarboxylic acid ammonium salt, Ammonium 1-pyrrolidinedithiocarboxylate, Ammonium N,N-tetramethylenedithiocarbamate, Ammonium pyrrolidine-1-dithiocarbamate, Ammonium pyrrolidine-N-dithiocarbamate, Ammonium pyrrolidinecarbodithioate, Ammonium pyrrolidinedithiocarboxylate, Pyrrolidine-N-dithiocarbamic Acid Ammonium
• Brand: TRC

Description

Applications 1-Pyrrolidinecarbodithioic Acid induces apoptosis in rat smooth muscle cells and inhibits apoptosis in leukemia HL-60 cells. It also prevents induction of nitric oxide synthetase by inhibiting translation of NOS mRNA;
References Cui, J., et al.: J. Biol. Chem., 285, 38951 (2010); Reid, P., et al.: Mol. Cancer, 8, 49 (2009)

Chemical properties

• Molecular weight: 164.29
• Formula: C₅H₁₂N₂S₂
• Color/Form: Neat
• InChI: InChI=1S/C5H9NS2.H3N/c7-5(8)6-3-1-2-4-6;/h1-4H2,(H,7,8);1H3
• InChI key: InChIKey=HAHGUNHNZVGBRD-HALIXAOFSA-N
• SMILES: CC1O[C@@H](O[C@H]2C(CO)O[C@@H](O[C@H]3C(CO)O[C@@H](O[C@@H]4OC(CO)[C@H](O)C(O)C4O)C(O)C3O)C(O)C2O)C(O)C(O)[C@H]1NC1C=C(CO)C(O)C(O)C1O