Pyropheophorbide A Methyl Ester

CAS: 6453-67-4

Ref. TR-P998865

Product Information

• Name: Pyropheophorbide A Methyl Ester
• Synonyms: 3-Phorbinepropanoic acid, 9-ethenyl-14-ethyl-4,8,13,18-tetramethyl-20-oxo-, methyl ester, (3S-trans)-, 3-Phorbinepropionic acid, 14-ethyl-4,8,13,18-tetramethyl-20-oxo-9-vinyl-, methyl ester (8CI), Pyropheophorbide a methyl ester (6CI,7CI), MePPP, Methyl pyrophaeophorbide a, Methyl pyropheophorbide a, NSC 267052, 3-Phorbinepropanoic acid, 9-ethenyl-14-ethyl-4,8,13,18-tetramethyl-20-oxo-, methyl ester, (3S,4S)-, Pyrophaeophorbide-a-monomethyl ester, Methyl 4-(9-Ethenyl-14-Ethyl-4,8,13-Trimethyl-20-Oxophorbin-3-Yl)Butanoate, Methyl 3-(9-Ethenyl-14-Ethyl-4,8,13,18-Tetramethyl-20-Oxo-24,25-Dihydrophorbin-3-Yl)Propanoate, Methyl pyropheophorbide-a

Description

Stability Light Sensitive
Applications Pyropheophorbide A Methyl Ester is a chlorophyll (C379815) analog for studies of photosynthesis. Methyl pyropheophorbide a (Pyropheophorbide-a methyl ester), a chlorophyll-a derivative, and is a potent photosensitizer that can be used in photodynamic therapy (PDT) of cancer. Methyl pyropheophorbide a has photodynamic activity and can induce apoptosis and inhibit tumor growth.
References Bensasson, R., et al.: Nature, 290, 329 (1981); Moore, A., et al.: Science, 216, 982 (1982)

• Brand: TRC

Chemical properties

• Molecular weight: 548.67
• Formula: C₃₄H₃₆N₄O₃
• Color/Form: Neat
• InChI: InChI=1S/C34H36N4O3/c1-8-20-16(3)24-13-26-18(5)22(10-11-31(40)41-7)33(37-26)23-12-30(39)32-19(6)27(38-34(23)32)15-29-21(9-2)17(4)25(36-29)14-28(20)35-24/h8,13-15,18,22,35,38H,1,9-12H2,2-7H3/b24-13-,25-14-,26-13-,27-15-,28-14-,29-15-,33-23-/t18-,22-/m0/s1
• InChI key: InChIKey=HYUPPKVFCGIMDB-UHFFFAOYSA-N
• SMILES: CCOC(=O)Cc1ccc(O)cc1