Ramatroban

CAS: 116649-85-5

Ref. TR-R109000

Product Information

• Name: Ramatroban
• Synonyms: 3-[(3R)-3-[(4-fluorophenyl)sulfonylamino]-1,2,3,4-tetrahydrocarbazol-9-yl]propanoic acid, (3R)-3-[[(4-Fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-carbazole-9-propanoic acid, 3-[(3R)-3-[(4-Fluorophenyl)sulfonylamino]-1,2,3,4-tetrahydrocarbazol-9-yl]propanoic acid, 3-[(3R)-3-{[(4-fluorophenyl)sulfonyl]amino}-1,2,3,4-tetrahydro-9H-carbazol-9-yl]propanoic acid, 3R-[[(4-Fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-carbazole-9-propanoic acid, 9H-Carbazole-9-propanoic acid, 3-[[(4-fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-, (3R)-, 9H-Carbazole-9-propanoic acid, 3-[[(4-fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-, (R)-, BAY-u 3405, Baynas

Description

Applications A thromboxane receptor antagonist for use in the treatment of coronary artery disease.
References Rahman, M., et al.: Int. Immunopharmacol., 6, 1736 (2006), Sato, T., et al.: J. Med. Chem., 51, 7705 (2008), Sandham, D., et al.: Bioorg. Med. Chem. Lett., 19, 4794 (2009),

• Brand: TRC

Chemical properties

• Molecular weight: 416.47
• Formula: C₂₁H₂₁FN₂O₄S
• Color/Form: Neat
• InChI: InChI=1S/C21H21FN2O4S/c22-14-5-8-16(9-6-14)29(27,28)23-15-7-10-20-18(13-15)17-3-1-2-4-19(17)24(20)12-11-21(25)26/h1-6,8-9,15,23H,7,10-13H2,(H,25,26)/t15-/m1/s1
• InChI key: InChIKey=LDXDSHIEDAPSSA-OAHLLOKOSA-N
• SMILES: O=C(O)CCn1c2c(c3ccccc31)C[C@H](NS(=O)(=O)c1ccc(F)cc1)CC2