Ramipril Diketopiperazine

CAS: 108731-95-9

Ref. TR-R111008

Product Information

• Name: Ramipril Diketopiperazine
• Synonyms: Ramipril Imp. D (EP), Ramipril USP Related Compound D, Ramipril USP RC D, Ethyl (2S)-2-[(3S,5aS,8aS,9aS)-3-Methyl-1,4-dioxodecahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-2-yl]-4-phenylbutanoate, Ramipril Related Compound D, Ramipril Impurity D, 2H-Cyclopenta[4,5]pyrrolo[1,2-a]pyrazine-2-acetic acid, decahydro-3-methyl-1,4-dioxo-α-(2-phenylethyl)-, ethyl ester, (αS,3S,5aS,8aS,9aS)-, 2H-Cyclopenta[4,5]pyrrolo[1,2-a]pyrazine-2-acetic acid, decahydro-3-methyl-1,4-dioxo-α-(2-phenylethyl)-, ethyl ester, [3S-[2(R*),3α,5aβ,8aβ,9aβ]]-, [3S-[2(R*),3a,5a,8a,9a]]-Decahydro-3-methyl-1,4-dioxo-a-(2-phenylethyl)-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazine-2-acetic Acid Ethyl Ester, [3S-[2(R*),3a,5ab,8ab,9ab]]-Decahydro-3-methyl-1,4-dioxo-a-(2-phenylethyl)-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazine-2-acetic Acid Ethyl Ester, Ramipril-diketopiperazine

Description

Impurity Ramipril EP Impurity D
Stability Hygroscopic
Applications Ramipril Diketopiperazine (Ramipril EP Impurity D) is a metabolite of Ramipril (R111000).
References Tabata, S., et al.: J. Biopharm. Sci., 1, 235 (1990),

• Brand: TRC

Chemical properties

• Molecular weight: 398.50
• Formula: C₂₃H₃₀N₂O₄
• Color/Form: White
• InChI: InChI=1S/C23H30N2O4/c1-3-29-23(28)19(13-12-16-8-5-4-6-9-16)24-15(2)21(26)25-18-11-7-10-17(18)14-20(25)22(24)27/h4-6,8-9,15,17-20H,3,7,10-14H2,1-2H3/t15-,17-,18-,19-,20-/m0/s1
• InChI key: InChIKey=KOVMAAYRBJCASY-JBDAPHQKSA-N
• SMILES: CCOC(=O)[C@H](CCc1ccccc1)N1C(=O)[C@@H]2C[C@@H]3CCC[C@@H]3N2C(=O)[C@@H]1C